Expression of Human Chorionic Gonadotropin (ßhCG) in Pre-eclamptic Placenta
نویسندگان
چکیده
منابع مشابه
Beta-Human Chorionic Gonadotropin (βHCG) Levels in Pre-eclamptic and Normotensive Pregnant Women
Background: Pre-eclampsia along with bleeding and infection constitute a triad that is a major cause of maternal mortality. Many factors have been recognized which can help us to determine the severity of the disease and early diagnosis of it. Since throphoblastic disorder is one of the etiological causes of pre-eclampsia, we decided to measure the level of β-hCG as a marker of detecting the ac...
متن کاملHuman chorionic gonadotropin-beta gene expression in first trimester placenta.
The hCGbeta gene family contains six genes linked in tandem on chromosome 19 and labeled beta genes 7, 8, 5, 1, 2, and 3. Previous studies on a small number of placentas have indicated that beta gene 5 was the most highly expressed gene during the first trimester of pregnancy, followed by genes 3 and 8. Beta genes 7, 1, and 2 were expressed at very low levels. The purpose of this study was to d...
متن کاملA Study of β-Human Chorionic Gonadotropin Level in Pre-Eclamptic and Normotensive Pregnant Women
Objectives: To study the role of β – hCG in pathogenesis of preeclampsia and its association with severity of preeclampsia. Materials and Methods: The prospective randomized study was conducted on 500 pregnant women of gestational pregnancy between 12 24 weeks with singleton pregnancy. According to American college of obstetrics and gynecology [ACOG, 2013], patients were classified into three g...
متن کاملIncreased cystatin C expression in the pre-eclamptic placenta.
Trophoblast invasion is regulated by proteinases and their inhibitors. Cystatin C inhibits cysteine proteinases. The serum concentration of cystatin C is increased in late pregnancy and pre-eclampsia. We aimed to investigate whether the expression of cystatin C is increased in the pre-eclamptic placenta and to investigate the expression pattern of cystatin C mRNA and protein in placental tissue...
متن کاملP-234: Expression of Human Chorionic Gonadotropin (hCG) Hormone Using Chinese Hamster Ovary Cells
Background: Human chorionic gonadotropin (hCG) is a member of glycoprotein hormones family consist of two different non-covalently heterodimeric chains: alpha and beta subunits with 92 and 145 amino acids respectively. This hormone plays an important role in human reproduction and physiology especially for maintenance of the corpus luteum during the first months of pregnancy Materials and Metho...
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ژورنال
عنوان ژورنال: International Journal of Morphology
سال: 2015
ISSN: 0717-9502
DOI: 10.4067/s0717-95022015000200031